As early as January 2021, the British Journal of Haematology reported a magical case in which a patient with Hodgkin’s lymphoma was infected with a novel coronavirus, and four months later, the tumor in his body turned magically almost disappeared. The researchers speculated that it may be that infection with the novel coronavirus triggered an anti-tumor immune response in patients, and the activated immune system successfully cleared cancer cells in the body.
Although this is only a special case, it also suggests that new coronavirus may have the potential to develop and transform into oncolytic virus.
Recently, researchers at Rush University Medical Center in the United States published a research paper entitled: Regression of Lung Cancer in Mice by Intranasal Administration of SARS-CoV-2 Spike S1 in Cancers Journal.
The study showed that the spike protein (S protein) of novel coronavirus (SARS-CoV-2) was able to cause apoptosis in lung cancer cells and inhibit tumor growth in a mouse model of lung cancer. This study suggests that the new coronavirus pandemic, which has plagued the world for three years, may lead to a new treatment for cancer.
We know that novel coronavirus invades human cells dependent on its spike protein (S protein) binding to the ACE2 protein on the surface of human cell, which play a key role in blood pressure and cellular process in human.
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